As a research scientist working in the Department of Human Genetics, you will be part of a team investigating the potential applications of custom-made oligonucleotide microarrays generated by a new, in-house developed system, the FlexArrayer from Flexgen. The project focuses on the design and selection of oligonucleotides for the arrays from (genomic) sequences, and, after array hybridisation, on the initial data analysis. Applications to be tested include gene expression, RNA-splicing, genome-tiling, re-sequencing and mutation detection. Your activities will include participation in the selection and/or development of appropriate software for the different phases of the project. The research project will be performed in close collaboration with the researchers applying the FlexArrayer in their project.

University Graduate
You hold a PhD, MSc or Higher Professional Education diploma in Molecular Biology or Bioinformatics and have a strong affiliation with molecular biological research in a multidisciplinary setting. You are familiar with basic techniques of molecular biology, such as molecular cloning, PCR, electrophoresis, labelling and hybridisation. You have experience with microarray-based technology, primer design, and possess programming skills. Since most studies do not provide training in this combination of skills, you are encouraged to apply if you graduated recently in Bioinformatics or followed a career in IT after an initial training in biology. An enthusiastic team player, you are also inquisitive, creative and ambitious. You are a good communicator and fluent in both written and spoken English.

LUMC Department of Human Genetics

The Department of Human Genetics is dedicated to the unravelling of the molecular mechanisms of hereditary disorders, the development and improvement of methods for diagnostic mutation screening, functional analysis of the genes involved using animal models and gene expression profiles and the development of gene therapy strategies. You will work within a dynamic research group of 20 post docs, PhD students and technicians.

Maximum salary amount in Euro's a month 3559
Employment basis: Temporary for specified period
Duration of the contract: one year
Maximum hours per week: 36

Additional conditions of employment:
You will be employed on the basis of a 36 hour week. Appointment is for one year, possibly to be extended. Employed as a research scientist, your salary will depend on your qualifications and experience, with a maximum of € 3.559,--gross per month based on a full time position (scale 10, according to the Collective Labour Agreement for University Hospitals).
With a Higher Professional Education Diploma you will be employed as a research analyst and you get a suitable offer according to the Collective Labour Agreement for University Hospitals

Additional information about the vacancy can be obtained from:

Dr. J.T. den Dunnen
Telephone number: +31 (0)71 5269501

Dr. P. Taschner
Telephone number: +31 (0)715269424

 
Or additional information can be obtained through one of the following links.

You can apply for this job before 22-06-2006 by sending your application to:

When applying for this job always mention the vacancy number E.06.GJ.31/AT.