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Netherlands: PhD student Nutrition
Written by Administrator
Friday, 29 June 2007
PhD student
Tasks: 1. Perform clinical permeability studies and
endoscopic biopsy methods to measure aspects of epithelial integrity and
epithelial permeability 2. Collect tissue material for transcriptomics and
proteomics analysis in the search and validation of biomarkers of integrity and
permeability 3. Use dietary and pharmaceutical intervention to study the role
of serotonergic signalling and the Enteric Nervous System in epithelial
integrity-related phenotypic changes 4. Assess secreted products of
enteroendocrine cells as biomarkers of intestinal epithelial
integrity.
Requirements
University Graduate Candidate profile Master’s
degree in Nutrition and Health or similar biomedical degree. Experience
and/or demonstrated interest in: ·intestinal physiology in particular
epithelial permeability ·nutrition research ·biochemical, cell biological,
and molecular biological techniques .transcriptomics, proteomics,
metabolomics, or other ‘omics’ approaches . bioinformatics
Additional information about the job: This PhD project
is part of a large and multidisciplinary project within TI Food&Nutrition
involving 5 postdocs, 5 PhD students and 2 technicians. This team is
supervised by 4 senior scientists with broad experience in the relevant
fields of research. The general aims are 1. to uncover by which mechanisms
nutrients and microorganisms have effects on the intestinal epithelial
integrity, 2. to identify relevant biomolecules that represent these
mechanisms, and to validate these as biomarkers for epithelial integrity, and
3. to develop these biomarkers into models that can be used to screen
nutrients for beneficial effect on the intestinal epithelium.
Organization
Top Institute Food and Nutrition
TI Food and Nutrition is a joint initiative of government,
industry and research institutes to strengthen the capacity for innovation and
the competitive strength of the Dutch food industry. TI Food and Nutrition
performs long-term strategic research at the highest level for the development
of new and innovated food products with attention to health aspects. Currently
five research institutes and seven major food companies participate. This
leading institute for Food Sciences gives the Dutch food industry the innovative
capacity to meet the challenges of the 21st century
Conditions of employment
Estimated maximum salary per month: eur 2000 -
2500 Salaryscale 10. Employment basis: Temporary for specified
period Duration of the contract: 1+ 3 years Maximum hours per week:
40
Additional conditions of employment: Appointement by
the University of Maastricht and labour conditions as for the dutch PhD's stated
by the VSNU. The work will be carried out within the a project of TI Food and
Nutrition.
Additional Information
Or additional information can be obtained through one
of the following links.
You can apply for this job before 12-07-2007 by sending
your application to:
TI Food and Nutrition drs. G.J.C. van Oosten
P.O.Box 557 6700 AN Wageningen The netherlands E-mail address:
see on the TIFN Internet for a projecte description and a
full jobdescription at vacancy A-1001.107
When applying for this job always mention the vacancy
number AT:A-1001.107
