UK: Post-doctoral Research Associate at Durham University
A Postdoctoral Research Associate is required to work on an EPSRC funded project involving the preparation of novel crystalline forms of pharmaceuticals via supramolecular gel phase crystallization methodologies.
This post forms part of a collaboration between Durham University and GSK concerning both supramolecular gel chemistry and microemulsion crystallization. This post is concerned with the gel phase aspects of the project and the postholder will collaborate with a parallel worker in microemulsion crystallization. The post holder will be required to undertake simple organic synthesis, tailoring gel formers to target pharmaceuticals and then undertake crystallization experiments within the new gels. Experience in gel characterisation using, for example rheology, would be a definite advantage.
The post holder will be involved with solid state characterisation using techniques such as XRPD, DSC, thermomicroscopy, IR and Raman spectroscopy. The post-holder will report to Prof. Jonathan W. Steed (PI), Dr. Sharon J. Cooper, Prof. Judith A. K. Howard FRS and Dr. Paul Hodgkinson.
These posts may require the applicants to spend some time at GSK’s Stevenage research centre to undertake crystallization studies on in development active pharmaceutical ingredients.
Primary technical responsibilities for the post includes the following.
Undertake gelator synthesis, and gel pharmaceutical crystallization studies. Undertake solid state characterisation of molecular organic solids and of gels using techniques such as XRPD, single crystal X-ray diffraction, rheology, IR and Raman spectroscopy, thermomicroscopy, electron microscopy. Analyse and interpret data. Prepare written and oral reports on progress and contribute to the preparation of beamtime applications for large scale facilities. Supervise PhD and MChem students in the laboratory. Oversee routine maintenance on local instrumentation and liaise with equipment service professionals. Liaise with collaborators at GSK.
Develop detailed programmes of work and assess progress against the work plan.
Keep comprehensive, accessible and secure records of experimental designs, data and analyses.
Prepare monthly and quarterly reports; participate in scheduled electronic and face-to-face meetings including presentation of research results. Organise and chair web-conferences if requested.
Present research presentations at national and international conferences.
Write or assist with the writing of papers for publication in international journals and conference proceedings.
Liaise effectively with members of the research team at Durham and GSK.