UK: Postdoctoral Scientist Bioinformatics and Imaging at MRC Harwell

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Ref: IRC114133

Salary: £26,545 – £30,184 per annum, plus £6,500 per annum Bioinformatics Allowance

Duration: Full Time – Fixed Term position to 31 July 2016

Description: We are seeking a postdoctoral scientist to join an NIH-funded project  (http://commonfund.nih.gov/KOMP2/index.aspx) at the Mammalian Genetics Unit (MGU), MRC Harwell in order to automate the annotation of morphological phenotypes from  advanced imaging technologies such as microCT and optical projection tomography (OPT).  This will be achieved through developing volume and shape analysis toolkits. In addition, you will be expected to explore different ways of presenting data visualisations online and to a variety of audience including clinical scientists.

The goal is to identify new mouse models for human congenital diseases through the automatic identification of mouse morphological phenotypes. Primary phenotype data will be collected under the auspices of the International Mouse Phenotyping Consortium (IMPC – http://www.mousephenotype.org/), with a large number of lines also available at MRC Harwell that disrupt embryonic development. In addition, we will be receiving large amounts of secondary phenotyping data from a variety of external collaborators.

To join us you will need:

  • A PhD in Computational Biology, or similar
  • Experience of 3D imaging modalities and image processing within the context of a biological model system
  • To be highly motivated to apply recent developments in mouse atlases and morphometric shape analysis to Harwell and IMPC mouse lines

You will work within the biocomputing team under the line management of Dr Henrik Westerberg. You will also work closely with the laboratories of Dr Andy Greenfield and Dr Dominic Norris, which will form part of the validation process of any novel techniques, and with Dr Lydia Teboul’s team, to develop sample preparation protocols to get the best data possible from our modalities. This is a new and exciting opportunity to work with a large number of collaborators,  a multitude of datatypes and to be part of a new rapidly growing group. Informal expressions of interest in this post can be sent to Dr Henrik Westerberg (h.westerberg@har.mrc.ac.uk). For further information about the Mammalian Genetics Unit visit www.har.mrc.ac.uk.

Applications are handled by the UK Shared Business Services; to apply please visit our job board,  and upload your CV along with a covering letter stating why you are applying for this role (when saving your documents please include the IRC number in the file name).  Applicants who would like to receive this advert in an alternative format (e.g. large print, Braille, audio or hard copy), or who are unable to apply online should contact us by telephone on 01793 867000. Please quote reference number IRC114133.

Benefits include a flexible pay and reward policy, excellent holiday entitlement, MRC final salary pension scheme.

Closing date: 10 November 2013
Interview date: Between 22 November and 28 November 2013

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