Netherlands: Postdoc position on Interaction of anti-freeze proteins with water and ice at FOM Institute AMOLF

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Job description

In this project we will study the molecular interactions between AFPs/AFGPs and water/ice that cause the freezing point depression. This study will be performed with advanced (nonlinear) spectroscopic techniques, like 2D polarization-resolved vibrational spectroscopy, surface sum-frequency generation and transient THz spectroscopy. These techniques enable the label-free study of the structural dynamics of the (glyco)protein conformations, the ice surfaces and the hydration shell of water molecules surrounding the protein.


Anti-freeze proteins (AFPs) and anti-freeze glycoproteins (AFGPs) have a surprisingly strong effect on the freezing point of water. Even millimolar concentrations are sufficient to lower the freezing temperature by 2 degrees Celsius. AFPs and AFGPs have evolved in fish, insects, plants, fungi and bacteria, and enable these organisms to survive in polar and near-polar areas. AFPs are also used in the food industry, for instance to prevent recrystallization in ice cream. Despite their apparent importance and industrial relevance, the mechanisms by which AFPs and AFGPs depress the freezing point of water are poorly understood


FOM prefers candidates who have qualifying experience (e.g. as PhD student or postdoctoral researcher) in a scientific research institute abroad.
Postdocs must meet the requirements for a doctors-degree and must have an MSc degree in physics or physical chemistry.

Conditions of employment

You will be employed by the FOM-foundation for a fixed period of three years. Your salary will be up to a maximum of 3.804 euro gross per month, depending on your level of experience.The salary is supplemented with a holiday allowance of 8% and an end-of-year bonus of 8,33%. The conditions of employment of the FOM-foundation are laid down in the Collective Labour Agreement for Research Centres (Cao-Onderzoekinstellingen), more exclusive information is available at this website under Personeelsinformatie (in Dutch) or underPersonnel (in English). General information about working at FOM can be found in the English part of this website under Personnel. The ‘FOM job interview code’ applies to this position.

Contract type: Temporary, three years


FOM Institute AMOLF

FOM Institute AMOLF, Amsterdam

Additional information


For information contact Prof.dr. Huib Bakker, Group leader Ultrafast Spectroscopy

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