USA: Postdoctoral Researcher Position at Center for Mitochondrial and Epigenomic Medicine

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DESCRIPTION: The Children’s Hospital of Philadelphia Research Institute is an interdisciplinary institution dedicated to conducting basic, clinical and translational research on conditions and diseases that affect children, and is part of The Children’s Hospital of Philadelphia and University of Pennsylvania research community.A postdoctoral researcher position is available in the laboratory of Dr. Marc Vermulst at the Center for Mitochondrial and Epigenomic Medicine at CHOP/UPenn.The primary goal of our laboratory is to understand the mechanistic basis of the aging process. Two projects are currently available:

Project 1: We have found that transcriptional errors cause proteotoxicity and the successful candidate will have an opportunity to follow up on our current findings, and to move our experiments into a transgenic mouse model. Extensive expertise in yeast genetics is required for this project, as well as a creative approach to science, and a strong motivation for aging research.

Project 2: We are using mitochondrial genetics, combined with massive, but detailed sequencing techniques to touch on stem cell behavior, tumor biology and the subcellular dynamics of mtDNA molecules in transgenic mouse models. The successful candidate must have a broad interest in mammalian cell biology, and experience with genomic approaches.

To support each of these projects, the candidate will have direct access to numerous research cores, as well as state-of-the-art equipment present in the Center for Mitochondrial and Epigenomic Medicine, which is headed by Dr. Douglas Wallace. CHOP has been voted the number one children’s hospital in the country in 2013, and is part of the University of Pennsylvania, one of the premier research institutions in the US. The successful candidate will work in an open lab space that is shared with, and supported by two other laboratories, and will work closely with the other members of the research team to achieve their goals.

Ph.D. in biomedical sciences or related fields, or M.D. with research experience required.
Experience working with yeast and mice preferred.


  • Excellent working ethics: honest, responsible, motivated, attentive to details, team spirit, and following high standard of science at CHOP.
  • Willingness and capability to both independently lead the project and work closely with colleagues.
  • Proficient skills of molecular biology, cell biology, biochemistry and genetics.
  • Communication and writing skills.

Postdocs will also be expected to acquire technical, lab management, and manuscript/grant writing skills; and participate in seminars, lectures, poster sessions and presentations at national meetings. Postdoctoral fellows also may be required to supervise junior lab members, develop new methods and protocols for research, and assist with the development of other research projects in the lab.The Postdoc experience will serve to extend, refine and enhance skills necessary for professional and career development, and will enable the individual to broaden his/her scientific background by acquiring new research capabilities. It is expected that this individual will conduct independent scholarly research, and will contribute directly to the overall research goals of the project and the research group.Postdocs will be expected to participate in project planning, recording and interpretation/evaluation of data, and communication of results.


  • Value for research integrity and collaborative research
  • High level of motivation
  • Effective problem solving/critical thinking skills
  • Ability to work independently
  • Ability to exercise discretion and judgment
  • Ability to perform assigned tasks with minimal supervision.
  • Ability to work accurately, works well with others, and pays strict attention to detail.
  • Must be adaptable to do work which is varied, and requires an intellectual and professional approach.
  • Strong interpersonal skills
  • Proficiency in the use of personal computers and software, including web-based database software (All Candidates must demonstrate proficiency with Microsoft Office Suite at time of interview)
  • Requires a high degree of flexibility of skills and hours.
  • Excellent written and verbal communication skills

– Child Abuse Clearances
– FBI Fingerprint Clearance
– Drug Screening
-Tobacco Screening
All CHOP employees who work in a patient building or who provide patient care are required to receive an annual influenza vaccine unless they are granted a medical or religious exemption.

To learn more about the CHOP Research Institute and the research programs visit:

To Apply:
Please e-mail your CV, including 2-3 references, to vermulstm(at) and CC postdocinfo(at)

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