Netherlands: PhD student in Early Lung cancer Detection with CT at Radboud University Nijmegen Medical Centre (RUN MC)

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Job description

Lung cancer is the most deadly cancer in men and women. Because most patients are diagnosed when the disease is already in an advanced stage, the 5-year survival rate is poor. With the advent of new generations multi-slice CT scanners, and their use in trials for lung cancer screening, we have learned that around 40% of all lung cancers have an early stage in which they are visible as a subsolid nodule on CT scans. If such precancerous lesions and early lung cancers are treated, survival rates approach 100%. But a too agressive management of such lesions also has risks. It may lead to overdiagnosis and overtreatment.

The goal of this project is to investigate the prevalence, malignancy rate, and long term outcome of subsolid nodules found on chest CT. Morphological characteristics, assessed by humans and by advanced computer analysis algorithms, that can predict malignancy and risk for death from lung cancer will be identified. The ultimate goal is to identify these incidental findings on chest CT that would lead to morbidity and mortality if left untreated, at a time when cure is possible and subsequent death from cancer can be avoided.

We are looking for an ambitious PhD student to work on this three year project that is funded by the Dutch Cancer Foundation. The work should result in a PhD thesis. This project is a collaboration between theDepartment of Radiology of Radboud University Nijmegen Medical Centre and the Department of Radiology of University Medical Center Utrecht, and the Diagnostic Image Analysis Group.


  • MSc degree (or equivalent) in Medicine
  • Strong interest in radiology and oncological research
  • Excellent communication skills in English, interest and capabilities to work in an interdisciplinary research team

Conditions of employment

  • Temporary, 3 years
  • 36 hour per week
  • Scale 10A: max € 38600 gross per year at full employment (incl. vacation bonus and end of year payments)


Radboud University Nijmegen Medical Centre (RUN MC)



Nijmegen is the oldest Dutch city with a rich history and one of the liveliest city centers in the Netherlands. Radboud University has over 17,000 students. Radboud University Nijmegen Medical Centre (RUNMC) is a leading academic center for medical science, education and health care with over 10,000 staff and 3,000 students.

Additional information

You will be appointed as a clinical PhD student at the Radboud University Medical Center Nijmegen, Department of Radiology, with the standard salary and secondary conditions for clinical PhD students in the Netherlands. You will work within the Institute for Oncology of Radboud University Nijmegen Medical Centre. Your performance will be evaluated after 1 year and will normally be extended by 2 years.

Applicants should include a CV, a list of followed courses and grades, a letter of motivation, and (preferable links to) your Master Thesis or any publications in English you have written.

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