Netherlands: PhD Photoacoustic Imaging

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Within the Biophysical Engineering Group of the
faculty, we are developing photoacoustic imaging to address the
limitations of the current technologies for breast cancer imaging. At
this moment in our advanced research program within the Biophysical
Engineering Group (BPE) with strong collaborations with the clinic, we
are poised to make a major impact on the breast imaging paradigm.
We have two vacancies in the team that will develop a new
instrument which enables full breast imaging on patients. The goal of
this instrument is to detect and/or diagnose breast cancer with high
resolution, sensitivity and reliability. This technology will be
demonstrated in a study of up to 60 abnormalities (invasive ductal
carcinomas and a sub-set of benign tumours) in patients.
The vacancies are for 1 PhD student and 1 Post-doctoral
researcher. The successful candidates in collaboration with a
technician and Masters students, will design and develop the
Photoacoustic Mammoscope (PAM-II) and participate in its validation on
patient trials. This will involve researching ultrasound detector
elements from collaborators and selecting the most suitable material
and architecture for a detector array. Further, design and development
of a patient-instrument interface will be undertaken including an
appropriate light delivery system. New image reconstruction algorithms
that incorporate corrections for acoustic heterogeneities and that
allow quantitation of optical absorption coefficient will be
implemented. Comprehensive testing of hardware and image reconstruction
algorithms will be done on phantoms. The instrument will at a certain
point be installed in the Breast Care facility of a hospital where the
clinical trials will take place.


University Graduate
PhD. Student requirements

The candidate has an excellent Master’s degree in Physics or
Engineering from a reputed university. Project experience in biomedical
optics or ultrasound is appreciated. Fluency in English is essential.
The assignment is for 4 years, with a go/no-go assessment at the
end of the 1st year. The candidate will disseminate results through
publications in journals and presentations at international
conferences. The employment period should be completed with a PhD
thesis. Vacancy number 08/271.


University of Twente Faculty of Science and Technology
Sharing knowledge, working together, research,
innovation. It is all part of the only campus university in the
Netherlands: the University of Twente (UT). A university with an
international character. We have for example many foreign doctoral
students, and master programmes are provided in English. Divided over 5
faculties, we provide more than 50 Bachelor and Master programmes,
varying from Applied Physics and Public Administration to Applied
Communication Science and Biomedical Technology. In beautiful green
surroundings, more than 8000 students and 2700 staff live, work and
recreate at the UT. It is also a place where talented people get every
opportunity to perform cutting edge research. But as an entrepreneurial
university this is not all we do. In ‘Kennispark’, for example, we work
together with the business community, we support our students in
setting up their own businesses and participate in many projects in the
area of knowledge development. In brief, a dynamic climate in which to
work and study.

The Faculty of Science and Technology (700
faculty members, 1100 students) offers a range of bachelor and master
courses (NanoTechnology, Applied Physics, Chemical Engineering and
Technical Medicine). The faculty’s research is organized in three of
the university’s interdisciplinary research institutes: MESA+, BMTI,
and IMPACT. These institutes increase the vitality of research by
enabling collaboration between programs and disciplines, by providing
shared facilities, and by attracting funding for joint projects. They
also provide a conduit to industrial partners and help in attracting
new faculty.

Conditions of employment

Estimated maximum salary per month: eur 2500 – 3000
Salaryscale 10.
Maximum salary amount in Euro’s a month 2558
Employment basis: Temporary for specified period
Duration of the contract: 4 years
Maximum hours per week: 38

Additional conditions of employment:
Our offer

We offer a top level research and academic environment with
excellent opportunities for personal development. We are part of the
research institute for Biomedical Technology (BMTI) which comprises
several groups housed in one building offering excellent shared
facilities. Participation in the activities of the BMTI such as
symposia and colloquia will expose one to cutting edge research in
related fields and offers opportunities for collaboration with other

The PhD student will earn a gross salary of €2,000/- pm in the 1st year to €2,558/- pm in the 4th year.

Additional Information

Additional information about the vacancy can be obtained from:

Dr. S. Manohar
E-mail address:

Prof. Van Leeuwen
E-mail address:

Or additional information can be obtained through one of the following links.

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You can apply for this job before 14-12-2008 by sending your application to:

University of Twente
faculty TNW
drs. M.D. Hilderink
Postbus 217
7500 AE Enschede

E-mail address:

When applying for this job always mention the vacancy number AT/08/271.


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