Netherlands: PhD student Radiology

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The PhD student carries out the research
project, aiming to identify non-invasive biomarkers to image
aggressiveness of prostate cancer by Magnetic Resonance.

•Publishes the results in scientific journals

•Accomplishes a PhD thesis

Requirements


University Graduate
A masters degree in (bio-) physics, chemistry, technical medicine, molecular sciences or a comparable training.

•Strong interest in or experience with MR

•An independent and well-structured working style

•Well developed communicative and social skills

•Permitted to work with mice (Art. 9)

Additional information about the job:
08730 PhD student

PhD student Molecular and functional Magnetic Resonance of prostate
cancer aggressiveness. Radboud University Nijmegen, Medical Center,
Nijmegen, The Netherlands

Department of Radiology:

Magnetic resonance (MR) is the major modality for non-invasive
investigations of anatomy, physiology and metabolism in humans and
animals. The development and application of novel MR methods for the
diagnosis, disease prediction and treatment monitoring of human cancers
is a main research focus at our department. We are one of the leading
groups in MR of prostate cancer, with many years of experience in this
field. This research is integrated with clinical examinations and other
investigations of prostate tissue to find the best solution for (bio-)
medical questions. Our cancer research is translational: to support
human studies with new perspectives and understanding, parallel MR
investigations are performed in animal models. The MR research group is
composed of senior researchers, PhD students and technical staff with
clinical, biological, bio-chemical, –physical, -engineering and
technical background. We collaborate intensively with the departments
of urology, pathology, radiotherapy, and nuclear medicine, and with
many groups at national and international level (e.g. in EU and US).
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Research facilities:

The Radboud University has the most extensive MR research equipment
in the Netherlands. For biomedical applications various systems are
available for imaging and spectroscopic purposes including 2 human 3T
whole body MR systems and a human 7T whole body MR. High-resolution NMR
machines up to 20 T are available at the science faculty. Pre-clinical
MR equipment (7 and 11.7 Tesla) is installed in a dedicated animal
imaging laboratory together with PET/CT and optical devices.

Job profile:

Prostate cancer is the most important cancer in man. As only
aggressive cancers are life threatening it is crucial to identify these
cases among the majority of indolent cancers, to select the best
therapy. However, no proper biomarkers to image cancer aggressiveness
have been established yet. Therefore the aim of this project is to
identify non-invasive biomarkers to image aggressiveness of prostate
cancer by Magnetic Resonance. Several novel ideas to identify
functional biomarkers for MR imaging will be explored. The project is
part of a larger research program "Exploring the clinical value of
novel high resolution anatomic and molecular / functional MR imaging in
prostate cancer" supported by the Dutch Cancer Society, which includes
several other subprograms focusing on detection, localization and
staging of prostate cancer. The candidate is expected to work in close
collaboration with the clinical and basic science researchers in the
other sub projects. You will perform molecular and functional imaging
on prostate in humans with MR and analysis of the results in the
context of other findings. The project may include complementary animal
or ex vivo tissue research. Part of the actual work will consist of the
development and implementation of quantitative MR methods, dedicated to
the specific research questions, both on human 3T and 7T whole body MR
systems. You are expected to participate actively in these developments
under supervision of senior researchers. For this purpose you will
learn the physics of spin system manipulation in living species and
additionally relevant prostate physiology and metabolism. At the end of
the project you will write a PhD thesis.

Requirements, position and salary:

We are looking for enthusiastic candidates with a Masters-degree in
(bio-) physics, chemistry, technical medicine, molecular sciences or a
comparable training. The multi-disciplinary character of the project
requires a broad interest and good communication skills. Strong
interest in or experience with MR is appreciated. We offer a fulltime
job for a period of 4 years. Salary according to the collective
agreement (CAO) of Dutch universities, scale 10A.

Contact Info:

Prof. dr. Arend Heerschap (Radiology department), phone
+31-24-3614795 (or +31-24-3614545), e-mail a.heerschap@rad.umcn.nl or
dr. Tom Scheenen (+31-24 3613157 ) and prof. dr. Jelle O. Barentsz
(+31-24 3617133)

Organization


University Medical Centre Nijmegen Radiologie

Magnetic resonance (MR) is the major modality
for non-invasive research of anatomy, physiology and metabolism in
humans and animals. The development and application of novel MR methods
for the diagnosis, disease prediction and treatment monitoring of human
cancers is a main research focus at our department. The radiology
department is one of the leading groups in MR of prostate cancer, with
many years of experience in this field.

Conditions of employment


Employment basis: Temporary for specified period
Duration of the contract: 4 years
Maximum hours per week: 36

Additional conditions of employment:
•Salary level 10A: maximal € 2572 gross per month

Additional Information


Additional information about the vacancy can be obtained from:

Prof. dr. Arend Heerschap, scientific researcher
Telephone number: (024) 3614795

Dr. Tom Scheenen, scientific reseacher
Telephone number: (024) 3613157

 
Or additional information can be obtained through one of the following links.

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Application


You can apply for this job before 22-08-2008 by sending your application to:

UMC St Radboud
227 COS
P. Claessen
Postbus 9101
6500 HB Nijmegen

E-mail address: solliciteren@clkf.umcn.nl

When applying for this job always mention the vacancy number AT 08730.

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